Gene name:
Fads2 (Fadsd6) ;
Protein name:
Fatty acid desaturase 2 ;
Alternative:
Delta(6) fatty acid desaturase (D6D;Delta(6) desaturase;Delta-6 desaturase) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the first and rate limiting step in this pathway which is the desaturation of LA (18:2n-6) and ALA (18:3n-3) into gamma-linoleic acid (GLA) (18:3n-6) and stearidonic acid (18:4n-3) respectively and other desaturation steps. Highly unsaturated fatty acids (HUFA) play pivotal roles in many biological functions.
Subcellular Location:
Endoplasmic reticulum membrane
Multi-pass membrane protein
Protein Attributes:
50:
MGKGGNQGEG | STELQAPMPT | FRWEEIQKHN | LRTDRWLVID | RKVYNVTKWS |
100:
QRHPGGHRVI | GHYSGEDATD | AFRAFHLDLD | FVGKFLKPLL | IGELAPEEPS |
150:
LDRGKSSQIT | EDFRALKKTA | EDMNLFKTNH | LFFFLLLSHI | IVMESIAWFI |
200:
LSYFGNGWIP | TVITAFVLAT | SQAQAGWLQH | DYGHLSVYKK | SIWNHIVHKF |
250:
VIGHLKGASA | NWWNHRHFQH | HAKPNIFHKD | PDIKSLHVFV | LGEWQPLEYG |
300:
KKKLKYLPYN | HQHEYFFLIG | PPLLIPMYFQ | YQIIMTMIRR | RDWVDLAWAI |
350:
SYYARFFYTY | IPFYGILGAL | VFLNFIRFLE | SHWFVWVTQM | NHIVMEIDLD |
400:
HYRDWFSSQL | AATCNVEQSF | FNDWFSGHLN | FQIEHHLFPT | MPRHNLHKIA |
444:
PLVKSLCAKH | GIEYQEKPLL | RALLDIVSSL | KKSGELWLDA | YLHK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Bovine
ELISA Kit for Rat Fatty acid desaturase 2
ELISA Kit for Rat Fatty acid desaturase 2
ELISA Kit for Rat Fatty acid desaturase 2
ELISA Kit for Rat Fatty acid desaturase 2
CLIA Kit for Rat Fatty acid desaturase 2
CLIA Kit for Rat Fatty acid desaturase 2
CLIA Kit for Rat Fatty acid desaturase 2
CLIA Kit for Rat Fatty acid desaturase 2
Polyclonal Antibody for Rat Fatty acid desaturase 2
Polyclonal Antibody for Rat Fatty acid desaturase 2
Polyclonal Antibody for Rat Fatty acid desaturase 2
Polyclonal Antibody for Rat Fatty acid desaturase 2
Monoclonal Antibody for Rat Fatty acid desaturase 2
Monoclonal Antibody for Rat Fatty acid desaturase 2
Monoclonal Antibody for Rat Fatty acid desaturase 2
Monoclonal Antibody for Rat Fatty acid desaturase 2
Protein for Rat Fatty acid desaturase 2
Protein for Rat Fatty acid desaturase 2
Protein for Rat Fatty acid desaturase 2
Protein for Rat Fatty acid desaturase 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
strain :
Sprague-Dawley .
tissue :
Liver .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];FUNCTION
strain :
Dark agouti .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Kidney .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INDUCTION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION